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Senna is one of the most often used herb in Ayurveda- traditional Indian system of health. It has a reputation as a powerful purging herb. Senna is a small, perennial, branched, drought resistant undershrub growing to a height of 60 - 75 cm. The leaves and green, immature pods contain glycosides like sennocides A and B, which are extensively used as a laxative particularly for habitual constipation Senna is a very strong laxative herb which may cause griping if used without other herbs. It is wise to use it in combination with warming, stimulating and antispasmodic herbs such as Ginger. Other appropriate herbs might include Cloves, Fennel, Cinnamon, and Coriander. It is important to realize that cathartic laxatives such as Senna should not be overused because this may lead to laxative dependency. Dietary changes, increased water intake, demulcent and bulk laxative herbs, and relaxation techniques should be explored before resorting to cathartic laxatives. In combination with other anthelminthic herbs it is used to expel intestinal worms. The principal active constituents of senna are dianthrone glycosides whose aglycone is Rhein. Rhein-induced laxative effects occur through two distinct mechanisms: an increase in intestinal fluid transport and an increase in intestinal motility.