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Long pepper (Piper longum), sometimes called Indian long pepper (Pipli), is a flowering vine in the family Piperaceae, cultivated for its fruit, which is usually dried and used as a herb, spice and seasoning. Pippali is known for Detoxifying the lungs. It helps in Removing Cold and Congestion.It also helps to Rejuvenate the Lungs and Kapha dosha, it even helps in expelling out the mucus accumulated in the respiratory tract.Trikatu (it contains Pippali as one of its three contents) is one of the most popular formulation used to mitigate the disease that occurs due to kapha dosha, it digest AMA (endotoxin) and it also increases the bioavailability of the drug , when it is used as a complementary medicine.It reduces the frequency of paroxysm, which causes the infection. Long pepper is known to contain the chemical compound piperlongumine.